- Alfred C. Payne Collection, 1917/20031
- Ann A. Hertzler Collection, 1863/2013, bulk 1974/20001
- Black Women at Virginia Tech Oral History Project Records, 1967/2000, bulk 1994/20001
- Charles Goodsell Collection, 1982/20011
- Dean Carter Papers, 1950/2003, bulk 1964/19821
- Doris Zallen Papers, 1952/20161
- Dr. Richard Zallen Papers, 1940/20071
- Earl A. Thornton Papers, 1885/20001
- Elizabeth Fine Papers, 1983/20121
- G. Preston Frazer Collection, 1939/20031
- Hard Times Blues Collection, 1966/20191
- Henry H. Bauer Papers,, 1950/20101
- Irving J. Good Papers, 1925/20041
- James I. Robertson Jr. Papers, 1849/20111
- Janet L. Cameron Collection,, 1931/20011