- Administration records collection, 1776/19761
- Beebe collection of Washington family papers, 1818/1861, bulk 1840/18501
- Brooke County (W. Va.) Court Records and Miscellaneous Papers, 1780/19181
- Bushrod Washington family papers, 1662/18351
- Contracts for the hiring of enslaved persons by the William Ackerly estate, 1860/18641
- George Washington collection, 1654/179946
- Gibson Lamb Cranmer Papers regarding Statehood and Other Material, 1787/1895, bulk 1822/18811
- Historic manuscript collection, 1601/193321
- Jane Isabella Watt White papers, 1848/20171
- John Augustine Washington III and Eleanor Love Selden correspondence, 1842/18601
- John Augustine Washington III and Mount Vernon Ladies' Association (MVLA) collection, 1834/19571
- John Augustine Washington III and family papers, 1789/199417
- John Walter Rice slavery documents, 1831/18321
- Kanawha County (W. Va.) Court Records and Miscellaneous Papers, 1773/19331
- Martha Washington collection, 1761/18021