- Beebe collection of Washington family papers, 1818/1861, bulk 1840/18501
- Bushrod Washington family papers, 1662/18351
- George Washington collection, 1654/179946
- Historic manuscript collection, 1601/193321
- John Augustine Washington III and Eleanor Love Selden correspondence, 1842/18601
- John Augustine Washington III and Mount Vernon Ladies' Association (MVLA) collection, 1834/19571
- John Augustine Washington III and family papers, 1789/199417
- Martha Washington collection, 1761/18021
- Peter family papers, 1722/19321
- Taylor collection of Lewis family papers, 1700/19501
- Ted and Mary Wendell early American collection, 1721/18261
- Wayne Rickert collection of founders' autographs, 1770/18311