- Albert Z. Conner collection, 1965/19661
- Beebe collection of Washington family papers, 1818/1861, bulk 1840/18501
- Betty Brown Clemmer and Willis Clemmer papers, 1920/2015, bulk 1943/19491
- Burtis Family Papers, 1847/19341
- Cadet drawings, class assignments, and exercises, 1849/19231
- Carl R. Dolmetsch Papers, 1751/19901
- Dorothy Lee Baugher papers, 1936/2003, bulk 1975/19811
- Drawings of Thomas Bewick, 18201
- Edwin Talley Agricultural Quadrangle Drawings, 20051
- Frederick S. Greene papers, 1914/19381
- George Washington collection, 1654/17992
- Harrisonburg Historic Map Collection, 1903/1982, bulk 1903/19561
- Historic manuscript collection, 1601/19334
- Historical Photograph Collection, 1850/20101
- James Taylor Drawing of the Wren Building and Yorktown, 18621