- Allard Hostetter Diaries, 1925/19491
- Andrew Jackson Dadisman (1881-1965), Agricultural Economics Professor, Papers, 1914/19631
- Bishop Robert E. Lee Strider Diaries, 1923/19701
- Brooke Family Papers, 1814/1990, bulk 1880/19601
- Brooks F. McCabe, Collector, Papers, 1770/20191
- Charles Brinkman, Collector, Papers, 1852/19521
- Clarence Edwin Smith (1885-1959) Papers, 1787/19572
- Edwards Family Papers, 1844/19511
- Ellison Family Papers, 1819/19771
- Elma H. Martin Papers, 1917/19791
- Frances Hunter Diary, 1930/19391
- George Seldon Wallace (1871-1963) Papers, 1898/19631
- George W. Johnson (1837-1902) Papers, 1860/19601
- H. B. Heiskell Travel Diary, 1847/19541
- Hardy County Papers, 1788/19411