- Henderson and Tomlinson Families Papers, 1789/18591
- Jacob M. Campbell Papers, 1796/18631
- James William Kuykendall Papers, 1765/19261
- John Pendleton Kennedy (1795-1870) Papers, 1829/18541
- John Pendleton Kennedy (1795-1870) Papers, 1829/18621
- John Smith, Methodist Circuit Rider, Journal, 1786/19631
- John and Robert Thompson Diaries, 1804/18631
- Lewis Family Papers, 1825/19361
- Logan Osborne Family and Business Records, 1761/19821
- Luke Wilcox (1795-1854) Diary, 1795/1879, bulk 1843/18541
- Luther Haymond, Surveyor, Diary and Surveyor's Book, 1830/18331
- Margaret M. Simon, Compiler, "Trips from Ohio to New Germany in Preston County, Virginia 1826, 1833, 1835", 1825/19861
- Max Mathers Collection Papers, 1821/19571
- Mrs. Lawrence M. Cox Papers, 1816/19401
- Nicholas Marmion, Physician, Family Papers, 1798/19511