- Historic manuscript collection, 1601/19337
- George Washington collection, 1654/17995
- Anderson Family papers, 1755/19581
- Barnhart Family Papers, 1836/19441
- Bowman Family Papers, 1765/19981
- Broome Family Papers, 1862/19951
- Brown, Coalter, Tucker Papers (III), 1838/19641
- Buckingham Female Collegiate Institute Indenture, 18541
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Charles Brown Papers, 1792/18881
- Claude Pierre Pecaudy de Contrecoeur Land Transfer, 17301
- Colonial Hotel Records, 1913/19301
- Deed between H. D. and Carrie Cole to Lucy R. Brooks, 19131
- Dillon Family Papers, 1805/19441
- Duncan Green Campbell Papers, 1789/18251