- Andrew Hollinger Papers, 1969/19771
- Betty E. Munger Correspondence, 1968/1991, bulk 1968/19801
- Collection of research materials about William R. Clark, 1950/20081
- Davidson Family Papers, 1870/19751
- Edward B. Hamer Correspondence, 1965/19731
- Effinger School Collection, 1909/20111
- Ellinor Porcher Gadsden Papers, 1839/19751
- Francis P. Gaines Papers, 1803/19791
- James Graham Leyburn collection, 1902/19932
- Jane Isabella Watt White papers, 1848/20171
- John Grier Varner Papers, 1905/1978, bulk 1926/19781
- John M. Godown collection, 1848/19781
- John W. Garrow Papers, 1899/19811
- Norman Franklin Lord Papers, 1946/2000, bulk 1970/20001
- Oscar B. Barker, Jr. Collection, 1890/1974, bulk 1920/19351