- Anderson Family papers, 1755/19581
- Ann Norvell Otey Scott Papers, 1920/19481
- Botts Family Correspondence, 1933/19461
- Campbell Family Papers, 1843/19501
- Carter Newman Bealer Papers, 1905/1962, bulk 1930/19501
- Charles Pomeroy Stone Family collection, 1880/19721
- Davidson Family Papers, 1870/19751
- Dillon Family Papers, 1805/19441
- Douglas Southall Freeman Correspondence, 1934/19361
- Edmund Charles Blunden Correspondence, 1934/19351
- Effinger School Collection, 1909/20111
- Ellinor Porcher Gadsden Papers, 1839/19751
- Elsie Ball Wright Bowley Papers, 1929/19721
- Fitzgerald Flournoy papers, 1912/19631
- Francis P. Gaines Papers, 1803/19791