- Anderson Family papers, 1755/19581
- Ann Norvell Otey Scott Papers, 1920/19481
- Baer Family Papers, 1744/19291
- Campbell Family Papers, 1843/19501
- Carter Newman Bealer Papers, 1905/1962, bulk 1930/19501
- Charles Pomeroy Stone Family collection, 1880/19721
- Davidson Family Papers, 1870/19751
- Dillon Family Papers, 1805/19441
- Edwin Luther Green Papers, 1865/19271
- Ellinor Porcher Gadsden Papers, 1839/19751
- Fitzgerald Flournoy papers, 1912/19631
- Francis P. Gaines Papers, 1803/19791
- Frank J. Gilliam Papers, 1914/19641
- Franklin Lafayette Riley Papers, 1897/19271
- George Washington collection, 1775/19491