- Robinson Family Papers, 1725/1940, bulk 1793/18481
- Short Papers, 1675/17891
- Ted and Mary Wendell early American collection, 1721/18261
- Thomas G. and Louise Rowe Pullen Collection, 1655/17911
- Tucker-Coleman papers, 1664/1945, bulk 1770/19071
- Tyler Family Papers, Group A, 1716/19461
- Tyler Family Papers, Group G, 1645/19171
- Tyler Family Papers, Group H, 1750/19351
- Upshur Family Papers, 1662/19361
- Virginia Cities Collection, 1663/19801
- Virginia Counties Collection, 1600/2000, bulk 1730/18901
- Waller family papers, 1677/19651
- Walter Jones Papers, 1721/17671
- William K. Perrin Papers, 1732/1902, bulk 1820/18581
- William Wiatt Papers, 1747/17851