- Armistead-Cocke Papers, 1680/19171
- Baird Family Papers, 1656/1922, bulk 1656/18481
- Bevill Family Papers, 1558/1939, bulk 1558/17071
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Carter Family Papers, 1667/1862, bulk 1792/18611
- Dunmore Family Papers (I) [in part photocopies], 1650/18991
- John Garland Pollard Papers, 1683/1968, bulk 1856/19371
- King William III and Queen Mary II Papers, 1689/17101
- Manuscripts - People and Family Names, 1621/1949, bulk 18001
- Robb-Bernard Papers, 1665/1980, bulk 1850/19501
- Short Papers, 1675/17891
- Thomas G. and Louise Rowe Pullen Collection, 1655/17911
- Tucker-Coleman papers, 1664/1945, bulk 1770/19071
- Tyler Family Papers, Group G, 1645/19171
- Upshur Family Papers, 1662/19361