- Amos Koontz Papers I, 1809/1965, bulk 1936/19651
- Arthur W. and Leah James Scrapbooks, 1909/19771
- Board of Visitors records, 1757/20231
- Carl A. "Pappy" Fehr papers, 1907/2012, bulk 1945/19741
- Catherine Dennis Papers, 1918/1974, bulk 1918/19211
- Class Histories and Activities collection, 1905/20141
- College Rules Collection, 1849/19551
- College of William and Mary Directory Collection, 1827/20131
- Commencement Exercises collection, 1831/20241
- Department of Military Science Records, 1918/20111
- Edwin Taliaferro Collection, 1860/19711
- Gregory Family papers, 1829/1920, bulk 1880/19001
- Hamilton Family Papers, 1892/2003, bulk 1930/20031
- Henderson Family Photographs, 1890/19291
- Herbert L. Ganter Papers, 1883/1979, bulk 1915/19651