- Gamble Papers, Letters and Photographs, 1774/18861
- Goshorn Family Papers, 1827/19261
- Harrison Hagans (1796-1867) Papers, 1810/18951
- Katherine Williams, Collector, Williams Family Papers, 1840/20051
- Reverend C. Shirley Donnelly Collection, 1731/1992, bulk 1860/19801
- Robinson Family Manuscripts, 1847/18831
- Roy Bird Cook (1886-1961), Collector, Tavenner Family Papers and Other Material, 1772/1955, bulk 1855/18661
- Roy Bird Cook, Collector, Tavenner Family Papers and Other Material, 1778/1953, bulk 1819/18841
- Southeastern West Virginia Historical Records, Civil War Letters and Other Material, 1825/1933, bulk 1833/18631
- Thomas Jonathan Jackson (1824-1863) Papers, 1845/18601
- Thornton Tayloe Perry, Collector, Papers, 1732/19651
- William K. Smith Family Papers, 1856/19121