- Baughman Family Papers, 1837/19681
- Bear Family Papers, 1823/18791
- Black, Kent, and Apperson Family Papers, 1779/19841
- Bobbitt Family Papers, 1825/19511
- Brotherton Family Collection, 1854/18871
- Brown Family Papers, 1825/1965, bulk 1850/18941
- Charles W. Crush Collection, 1796/19781
- Charles W. Hardin Collection, 1847/18831
- Charlton Family Papers, 1853/19581
- Dorothy H. Bodell Papers, 1850/19961
- Earhart Family Papers, 1788/19281
- Edwin Houston Harman Papers, 1856/1984, bulk 1856/18641
- Gresham Family Papers, 1825/19431
- Harper's Weekly Civil War Illustrations, 1851/18641
- Henry Iddings Family Collection, 1810/19001