- Bear Family Papers, 1823/18791
- Black, Kent, and Apperson Family Papers, 1779/19841
- Bobbitt Family Papers, 1825/19511
- Brown Family Papers, 1825/1965, bulk 1850/18941
- Charles W. Crush Collection, 1796/19781
- Earhart Family Papers, 1788/19281
- Gresham Family Papers, 1825/19431
- Henry Iddings Family Collection, 1810/19001
- Huff-Hylton Families Papers, 1803/19751
- Isaac Horne Ledgers, 1824/18701
- Jamerson-Webster-Basham Family Papers, 1792/19361
- Jeremiah White Graves Diary, 1820/18781
- John Janney Papers,, 1811/1994, bulk 1840/18801
- Key Family Papers, 1812/19041
- Martha L. Johnson Family Papers, 1821/18821