- Adam Empie Papers, 1811/2004, bulk 1811/18501
- Amos Koontz Papers I, 1809/1965, bulk 1936/19651
- Bell Hospital Records, 1926/19701
- Blow Family Papers, 1613/1960, bulk 1770/18751
- Bozarth Family Papers, 1931/1985, bulk 1931/19621
- Chappelear Collection, 1788/19591
- Davis and Bower City Meat Market (Charleston, Ill.) Account Book, 1875-1878, 1875/19781
- Diggs Family Papers, 1914/1960, bulk 1920/19401
- Ernest Stuart Elsea Ledgers, 1944/19681
- George Smith Papers, 1862/19541
- Hall Family Papers, 1810/20071
- Ivy House Restaurant Records, 1906/1985, bulk 1948/19601
- Office of the Bursar Records, 1739/19871
- Person Family papers, 1872/20021
- Rembert Family Papers, 1885/1965, bulk 1910/19551